In 1868, François Leroy founded Maison Leroy. One of his descendants, Henri, bought half of the Romanée-Conti vineyard in 1942, an estate with great notoriety whose wines are still famous throughout the world.
In 1971, his daughter Lalou Bize-Leroy took over the management of Maison Leroy and was also co-manager of the Romanée Conti estate from 1974 to 1992. It was not until 1988 that the estate was created in the Côtes-de Nuit appellation. after purchasing the vines from Domaine Noëllat and from Domaine Philippe Rémy. From September 1988, all of the estate's vines were cultivated and cared for using biodynamic methods.